in August 2020 (volume 23, No. 2), p. 91 - 96
Authors L. Verzeaux, R. Vyumvuhore, L. Marchand, S. Bordes, E. Aymard, and B. Closs
In a previous study, the molecular signature of graying hair was established by confocal Raman microspectroscopy. A specific signature in gray hair was described and new markers like lipid organization and protein conformation were identified.
Based on these discoveries, a natural active ingredient was developed to regulate hair graying. This active was able to stimulate melanin production and to detoxify gray hair through the innovative process of autophagy. Consequently, the natural active ingredient reduces H2O2 content in the hair shaft, as well as amino acids oxidation and improves the structural quality of the hair.
This active ingredient, commercialized under the name of AGREYNIST®, is anti-free radical and pro-pigmenting and enables greying hair to return to its natural color without the need of dyeing it.