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3D models of reconstructed skin

A breakthrough for clinical proof of efficacy

SILAB has deposited the SILABSKIN® trademark, the result of the company’s experience in the technology of 3D models, mimicking skin architecture. These multi-layer in vitro models (reconstructed epidermis or full thickness skin) are an essential link in the chain of proof of the efficacy of natural active ingredients offered to the cosmetic and dermo-cosmetic markets.

Each step has its requirement

The methodologies implemented are robust and SILAB is committed to three levels of requirements: traceability of the biological material, in-house control of skills and methods, and the quality and reproducibility of models. This requires standardized protocols and a suitable environment, along with modern equipment and high-tech analyses such as "omics".

Models of "normal or compromised" skin

SILAB’s experts of the in vitro platform have developed innovative 3D models, mimicking specific biological realities (aging, photo-aging, nutritional deficiency, chemical aggression, atopy, etc.). Thanks to the full control of this state of the art technology, SILAB initiated the modeling of compromised skin. The results of this research have been published in the British Journal of Dermatology1, proof of SILAB’s elevated scientific level in the sophistication of biological 3D models.
1 Rouaud-Tinguely et al., From the morphologic to the transcriptomic characterization of a compromised 3D in vitro model mimicking atopic dermatitis, British Journal of Dermatology, 2015.

Our news about this expertise

Original in-house models...

In vitro. For its first active ingredient designed to treat atopic dermatitis, SILAB softcare Research developed compromised SILABSKIN® RE reconstructed epidermis models, which mimic the biological...

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SILABSKIN®, proven expertise in reconstructed 3D biological models

For several years, SILAB Research has been working on the development, validation and culturing of human cells in 3D. These multi-layer in vitro models, known either as reconstructed epidermises or...

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