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37 results for tag « publication »


A natural concentrate to relieve sensitive skin

 Thursday 19 December 2019

Every day, external stimuli, such as climate and pollution, cause excessive reactions in sensitive skin. They are subjected to stinging sensations, redness, burning and tightness. Bio-inspired by the red sage, a plant used in traditional Chinese medicine and known for its high capacity to resist very low temperatures, SILAB developed a natural active ingredient able to treat skin discomfort of sensitive skin by targeting for the first time the three biological components of skin sensitivity: neuronal hyper-reactivity, alteration of the barrier function and chronic inflammation.

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SILAB and the team of Professor Aberdam reveal the key role of exosomes in hair growth

 Monday 07 October 2019

For the first time, SILAB and the team of Prof. Aberdam have shown that exosomal communication between the dermis and the hair follicle is an interesting biological pathway for the growth of hair. This work has just been published in the highly respected journal Stem Cells, following a peer-review process by experts in the field.



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SILAB publishes a clinical study conducted on atopic patients

 Thursday 12 September 2019

SILAB Softcare research teams have demonstrated the clinical efficacy of fructosans from Ophiopogon japonicus in the reduction of flares of atopic dermatitis in Caucasian patients. This clinical study has just been published in the journal Acta Dermato-Venereologica*, following a peer-review process by experts in the field.

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Identification of miRNA-22-5p and miRNA-199a-5p as epigenetic targets to fight against environmental skin aging

 Wednesday 11 September 2019

The understanding of epigenetics mechanisms underlying transcriptomic modulations during skin stress has become a major priority for dermo-cosmetics research. In this context, SILAB aimed to study and correlate modulations in the miRNA profile (miRNome) with modifications of the mRNA profile (transcriptome) in human fibroblasts submitted to repetitive doses of solar simulated radiations (SSR) to induce irradiation-induced stress phenotype. SILAB performed an original screen of irradiation-regulated miRNAs in human fibroblasts that allowed the identification of two new miRNA-mRNA interactions mediating irradiation-induced stress.

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Structure-function relationship between a natural cosmetic active ingredient and the olfactory receptor OR2AT4

 Tuesday 26 March 2019

Although the olfactory receptor OR2AT4 has been described as involved in epidermal renewal, there is no data up to date about a cosmetic active ingredient able to activate this receptor. This research work thus revealed a natural molecule capable of binding to this OR2AT4 receptor in order to stimulate keratinocyte migration.

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