Clinical efficacy
The healing efficacy of CICACTYL® was clinically demonstrated in a cohort of adult Caucasian subjects with damaged skin. By acting as of the first applications, CICACTYL® promotes recovery of the skin barrier. As a result of this rapid action, erythema, drying and scabs are attenuated, showing a positive action on the quality of healing.
Pharmacological activities
Novel in vitro models highlighted the capacity of CICACTYL® to improve skin repair dynamics by targeting the four biological events in the proliferation phase:
- the formation of granulation tissue is supported;
- the vascular network is improved;
- re-epithelialization of the wound is stimulated;
- inflammation is reduced.
Provided with this multi-target action, the active ingredient significantly improves the rate of healing.
Naturality
CICACTYL® is a natural active ingredient 85% purified in galactomannans, obtained from carob gum (Ceratonia siliqua). It has a natural origin content of 100% (ISO 16128).
The results of studies have shown that the efficacy of CICACTYL® depends on the size, the structure and the origin of the galactomannans. The latter have a strong affinity for lectins and one receptor, described as having a beneficial effect on the healing process.
In order to secure a sustainable supply of carob gum, SILAB has created partnerships with several suppliers in the Mediterranean basin certified for organic agriculture and who provide carob gum whose quality is perfectly controlled.
Ceratonia siliqua
Safety
CICACTYL® (INCI name: Galactomannan & Maltodextrin) is perfectly tolerated by wounded or damaged skin requiring repair. A preservative-free powder (recommended amount: 0.05 to 1%) and without harmful or potentially allergenic substances, this active ingredient is recommended in healing cosmetic and dermo-cosmetic facial and body care products intended for adults (including pregnant and breast-feeding women) and infants.
